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. 2014 Nov;351(2):440–447. doi: 10.1124/jpet.114.218966

Fig. 4.

Fig. 4.

Acute l-dopa and dopamine tissue content in the DRN. Dopamine, DOPAC, and HVA tissue content in the DRN was measured 45 minutes after l-dopa injection. (A and B) Acute l-dopa significantly elevated dopamine and its metabolites in both the dorsal and ventral DRN compared with vehicle. (C) The magnitude of dopamine increase after acute l-dopa did not differ between dorsal and ventral DRN. (D) The DOPAC/dopamine ratio was significantly greater in the dorsal compared with ventral DRN after acute l-dopa. (*P < 0.05 compared with vehicle controls; #P < 0.05 compared with ventral DRN, Student’s t test) (n = 6 per group).