Fig. 1.

Depicts the mean (±S.E.M.) average number of infusions self-administered directly into the pVTA during sessions 1–4 in adolescent naïve subjects (left) and adolescent drinkers (right). *Indicates significantly more infusions than aCSF controls. +Indicates significantly more infusions than aCSF controls and corresponding adolescent naïve group. ^Indicates significantly more infusions than aCSF controls and 50 mg% group (adolescent naïve, n = 6–10/group; adolescent drinkers, n = 7–10/group).