Fig. 1.
Systolic blood pressure (BP), mean arterial pressure, diastolic BP, heart rate, and pulse pressure measured by telemetry in conscious DS rats maintained on a HF/HS diet during a 4-week course of study. Separate groups were given vehicle, the ETA receptor antagonist, ABT-627 (ABT), or the diuretic, CLTD. Group effects are indicated as *P < 0.05 versus control; †P < 0.05 versus ABT alone. n = 6 each group. Comparisons between individual groups on individual days are indicated in the inset table (P < 0.05 for specific days indicated).