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Determination of glomerular injury as assessed by measurement of proteinuria (A), albuminuria (B), and nephrinuria (C) in DS rats on a HF/HS diet treated with vehicle, ABT, CLTD, and ABT + CLTD for 4 weeks. Tubulointerstitial injury was assessed by measuring urinary KIM-1 excretion (D). *P < 0.05 versus control; †P < 0.05 versus ABT alone.
