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. 2014 Oct 15;28(20):2276–2290. doi: 10.1101/gad.248492.114

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© 2014 Gwon et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 7. — Structural comparison of four flap structure-selective nucleases. Four structure-selective nucleases were compared: PaFAN1 (A), hFEN1-DNA (3Q8K) (B), hExo1-DNA (3QEB) (C), and hMUS81-DNA (4P0S and 4P0R) (D). Post-nick DNA is in the same orientation. The wedge helix is shown in green. (E) Surface representation of PaFAN1 bound to 5′ flap DNA. A hole is marked. The figure is an orthogonal view of A. (F) Surface representation of hFEN1 with 5′ flap DNA. The figure is an orthogonal view of B.