Table 1.

DEOP statistics

Type	Count
Osmoprotectants	109
Orphan osmoprotectantsa	34
Candidate osmoprotectantsb	3
Osmoprotection relatedc	23
Other compoundsd	2738
Pathways	834
Reactions affecting one or more osmoprotectants	1883
Other reactionse	2166
Genes	3529
Enzymes	4899
Organisms	1160

^aAn orphan osmoprotectant is one that we could not link to a metabolic pathway.

^bA candidate osmoprotectant is one that was reported to accumulate in a microorganism under stress but was not labelled as an osmoprotectant.

^cCompounds that play a role in the osmoprotection response but are not accumulated as osmolytes.

^dOther compounds in a reaction in which a curated osmoprotectant is involved.

^eReactions that are part of a pathway in which one or more osmoprotectants are involved, but these reactions do not directly affect any of the osmoprotectants.