Table 3. TEA trial: differences in DDD per 1000 patients of prescribed drugs (intervention vs control: 1605 included GPs).
Absolute mean prescriptionduring follow-up in the ‘intervention group’ (DDD per 1000assisted population/day) | Absolute difference atfollow-up vs control group (change from baselineexpressed as DDD per 1000 assisted population/day) | Relative % variationvs control: m-ITT(95% CI) | |
Primary outcomes (arm 1: BPH) | |||
finasteride+dutasteride | 6.61 | 0.24 | 3.6% (−2.9 to 10.2%) |
alfuzosin vs tamsulosin +terazosin † | 0.71 (ratio) | −0.06 | −8.5% (−16.9 to −0.7%) |
Secondary outcomes (arm 1: BPH) | |||
finasteride | 3.60 | 0.05 | 1.4% (−6.5 to 9.5%) |
dutasteride | 3.00 | 0.18 | 5.8% (−2.6 to 14.3%) |
alfuzosin | 6.82 | −0.11 | −1.7% (−8.9 to 5.6%) |
tamsulosin | 7.92 | 0.28 | 3.7% (−3.1 to 10.4%) |
terazosin | 3.21 | 0.17 | 5.4% (−4.1 to 14.6%) |
Primary outcomes (arm 2: osteoporosis) | |||
alendronate | 4.99 | <0.01 | 0.1% (−7.3 to 7.5%) |
risedronate | 2.03 | −0.11 | −5.1% (−15.3 to 5.6%) |
Secondary outcomes (arm 2: osteoporosis) | |||
ibandronate | 0.48 | −0.11 | −19.6% (−33.9 to −5.4%) |
alendronate vs risedronate + ibandronate § | 2.89 (ratio) | 0.27 | 10.4% (−3.5 to 24.6%) |
strontium ranelate | 0.59 | 0.03 | 4.8% (−12.9 to 21.0%) |
raloxifene | 0.13 | <0.01 | 0.4% (−26.9 to 27.5%) |
calcium | 1.83 | −0.11 | −5.4% (−15.6 to 5.4%) |
vitamin D | 1.72 | −0.06 | −3.5% (−12.4 to 5.3%) |
56 physicians who had not prescribed tamsulosin or terazosin could not be included in the calculation since this is a ratio.
300 physicians who had not prescribed risedronate or ibandronate could not be included in the calculation since this is a ratio.