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. 2014 Oct 17;9(10):e109915. doi: 10.1371/journal.pone.0109915

Table 3. TEA trial: differences in DDD per 1000 patients of prescribed drugs (intervention vs control: 1605 included GPs).

Absolute mean prescriptionduring follow-up in the ‘intervention group’ (DDD per 1000assisted population/day) Absolute difference atfollow-up vs control group (change from baselineexpressed as DDD per 1000 assisted population/day) Relative % variationvs control: m-ITT(95% CI)
Primary outcomes (arm 1: BPH)
finasteride+dutasteride 6.61 0.24 3.6% (−2.9 to 10.2%)
alfuzosin vs tamsulosin +terazosin 0.71 (ratio) −0.06 −8.5% (−16.9 to −0.7%)
Secondary outcomes (arm 1: BPH)
finasteride 3.60 0.05 1.4% (−6.5 to 9.5%)
dutasteride 3.00 0.18 5.8% (−2.6 to 14.3%)
alfuzosin 6.82 −0.11 −1.7% (−8.9 to 5.6%)
tamsulosin 7.92 0.28 3.7% (−3.1 to 10.4%)
terazosin 3.21 0.17 5.4% (−4.1 to 14.6%)
Primary outcomes (arm 2: osteoporosis)
alendronate 4.99 <0.01 0.1% (−7.3 to 7.5%)
risedronate 2.03 −0.11 −5.1% (−15.3 to 5.6%)
Secondary outcomes (arm 2: osteoporosis)
ibandronate 0.48 −0.11 −19.6% (−33.9 to −5.4%)
alendronate vs risedronate + ibandronate § 2.89 (ratio) 0.27 10.4% (−3.5 to 24.6%)
strontium ranelate 0.59 0.03 4.8% (−12.9 to 21.0%)
raloxifene 0.13 <0.01 0.4% (−26.9 to 27.5%)
calcium 1.83 −0.11 −5.4% (−15.6 to 5.4%)
vitamin D 1.72 −0.06 −3.5% (−12.4 to 5.3%)

56 physicians who had not prescribed tamsulosin or terazosin could not be included in the calculation since this is a ratio.

§

300 physicians who had not prescribed risedronate or ibandronate could not be included in the calculation since this is a ratio.