Table 3. Recombinant allergens differentially recognize venom allergic patients.
| Allergic Patients | |||||||||||
| Specific IgE | BAT | ||||||||||
| Patient | Skintest | nVenom≥0.35 KU/L | V1≥0.1 O.D | V2≥0.1O.D. | V3≥0.1O.D. | V5≥0.35 KU/L | nVenom≥15.7% | V1≥15.7% | V2≥15.7% | V3≥15.7% | V5≥15.7% |
| 1 | + | + | + | − | − | + | + | N.D. | N.D. | N.D. | + |
| 2 | + | + | + | − | − | + | − | N.D. | N.D. | N.D. | − |
| 3 | + | + | + | − | − | + | + | N.D. | N.D. | N.D. | + |
| 4 | + | + | + | + | + | − | N.D. | N.D. | N.D. | N.D. | N.D. |
| 5 | + | + | + | − | + | + | − | N.D. | N.D. | N.D. | + |
| 6 | + | + | + | + | + | + | + | N.D. | N.D. | N.D. | + |
| 7 | + | + | + | − | − | + | + | N.D. | N.D. | N.D. | − |
| 8 | + | + | + | + | + | + | + | N.D. | N.D. | N.D. | + |
| 9 | + | + | + | − | + | + | + | N.D. | N.D. | N.D. | + |
| 10 | + | + | + | + | + | + | + | N.D. | N.D. | N.D. | + |
| 11 | + | + | − | − | − | − | + | N.D. | N.D. | N.D. | N.D. |
| 12 | + | + | − | − | − | − | + | − | − | − | + |
| 13 | + | + | − | + | + | − | − | − | − | − | − |
| 14 | + | + | − | − | − | + | + | − | − | + | + |
| 15 | + | + | N.D. | N.D. | N.D. | + | + | − | − | − | + |
| 16 | + | + | − | − | + | + | + | − | − | + | + |
| 17 | + | + | N.D. | N.D. | N.D. | + | + | − | + | + | + |
| 18 | + | + | − | − | − | + | + | − | − | − | + |
| 19 | + | + | − | − | − | + | + | − | − | − | + |
| 20 | + | + | − | − | − | + | + | − | + | + | + |
| 21 | + | + | − | − | − | + | + | − | + | + | + |
| 22 | + | + | + | − | − | + | N.D. | N.D. | N.D. | + | N.D. |
| 23 | + | + | + | + | + | + | + | + | + | + | + |
| 24 | + | + | − | − | − | + | − | − | − | − | + |
| 25 | + | + | + | + | + | + | − | − | − | − | + |
| 26 | + | + | − | + | + | N.D. | − | − | − | + | + |
| 27 | + | + | − | − | + | + | − | − | − | + | + |
| 28 | + | + | + | − | − | N.D. | − | − | − | + | + |
| 29 | − | + | + | + | + | − | − | + | + | + | + |
| 30 | + | + | + | − | − | + | + | + | + | + | + |
| 31 | + | + | + | + | − | + | + | + | + | − | + |
| 32 | + | + | + | + | + | + | − | − | − | − | − |
| 33 | + | + | N.D. | N.D. | N.D. | + | + | − | − | − | + |
| 34 | + | + | + | − | − | + | + | − | − | − | + |
| 35 | + | + | + | + | + | − | + | − | − | − | + |
| 36 | + | + | + | − | − | + | + | + | − | + | − |
| 37 | + | − | N.D. | N.D. | N.D. | + | + | + | + | + | + |
| 38 | + | + | + | + | + | + | + | N.D. | N.D. | N.D. | N.D. |
| 39 | − | + | − | + | − | − | − | − | − | − | − |
| 40 | + | + | N.D. | N.D. | N.D. | + | − | − | − | − | − |
| 41 | + | + | + | + | − | + | + | − | + | + | + |
| 42 | + | + | − | − | − | − | + | + | + | + | + |
| 43 | + | + | + | + | + | − | − | − | − | N.D. | N.D. |
| Control Group | |||||||||||
| 1 | N.D. | − | − | − | − | − | − | − | − | − | − |
| 2 | N.D. | N.D. | N.D. | − | − | − | − | − | − | − | − |
| 3 | N.D. | − | + | + | + | − | − | − | + | − | − |
| 4 | N.D. | − | − | − | − | − | − | − | − | − | − |
| 5 | N.D. | − | − | − | − | − | − | − | − | − | − |
| 6 | N.D. | − | − | − | − | − | − | − | + | − | − |
| 7 | N.D. | − | N.D. | N.D. | N.D. | + | + | − | − | − | − |
| 8 | N.D. | − | + | + | − | − | − | − | − | − | − |
| 9 | N.D. | − | − | − | − | − | − | − | − | − | − |
| 10 | N.D. | N.D. | + | + | − | − | − | − | − | − | − |
| 11 | N.D. | − | − | − | − | − | − | − | − | − | − |
| 12 | N.D. | N.D. | − | − | − | − | − | − | − | − | − |
| 13 | N.D. | − | + | + | − | − | − | − | − | − | − |
| 14 | N.D. | − | + | + | + | − | − | − | − | − | − |
| 15 | N.D. | + | + | + | + | − | − | − | − | − | − |
| 16 | N.D. | + | + | + | + | − | − | − | − | − | − |
| 17 | N.D. | + | + | − | − | + | − | − | − | − | − |
Table legend: nVenom = natural venom, V1 = rVes v 1 V2 = rVes v 2 V3 = rVes v 3, V5 = rVes v 5; “+” = positive patient; “–“ = negative patient; N.D. = not done: sIgE = specific IgE; BAT = Basophil activation test. Cut-offs: 0.35 KU/L ImmunoCaps, 0.1 O.D. ELISAs, 15.7% CD63 expression in BAT. Empty spaces indicate untested samples.