Table 5. Association between the expression of Toll-like receptors (TLR-2/4) and the production of cytokines (in quartiles) in 311 postmenopausal women.
ORa | 95%IC | P valueb | |
TLR-2 | |||
IL-1β, P75 | 1.99 | 0.98–4.04 | 0.06 |
IL-6, P75 | 2.21 | 1.14–4.27 | 0.01 |
IL-10, P25 | 2.03 | 1.01–4.10 | 0.04 |
TNF-α, P75 | 1.88 | 1.01–3.54 | 0.04 |
TLR-4 | |||
IL-1β, P75 | 2.13 | 0.85–5.37 | 0.10 |
IL-6, P75 | 2.95 | 1.26–6.90 | 0.01 |
IL-10, P25 | 1.15 | 0.52–2.54 | 0.71 |
TNF-α, P75 | 0.83 | 0.42–1.65 | 0.60 |
TLRs, Toll like receptor 2 and 4; IL, interleukins (pg/mL); TNF tumor necrosis factor (pg/mL); P75, percentile 75; P25, percentile 25.
Adjusted results for age, time since menopause, body mass index and physical activity.
Significant difference p<0.05 (linear regression model).