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. Author manuscript; available in PMC: 2015 Oct 15.
Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Aug 28;969:235–240. doi: 10.1016/j.jchromb.2014.08.030

Fig. 2.

Fig. 2

Representative multiple reaction monitoring chromatograms of (A) blank mouse plasma, (B) mouse plasma spiked with SP-157 (IS, 16.2 ng/mL), (C) mouse plasma spiked with SP-141 (0.648 ng/mL, LLOQ) and SP-157 (16.2 ng/mL), (D) mouse plasma spiked with SP-141 (64.8 ng/mL) and SP-157 (16.2 ng/mL), and (E) plasma sample from CD-1 mouse 0.083 h (5 mins) after single i.v. dose of 40 mg/kg SP-141 plus SP-157 (16.2 ng/mL).