(a, b) Unsupervised hierarchical clustering of Group 3 MB samples profiled by Affymetrix gene expression array (a) or Illumina 450K DNA methylation array (b). (c) Patient characteristics, including age, gender, histological subtype (histology), and metastatic status (M-stage) for Group 3 MBs stratified according to GFI1/GFI1B expression status. Both gene expression and IHC cohorts are summarized. (d, e) Overall survival of Group 3 MBs stratified by GFI1/GFI1B expression status for both our gene expression (d) and IHC series (e).