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. Author manuscript; available in PMC: 2015 Jul 24.
Published in final edited form as: Nature. 2014 Jun 22;511(7510):428–434. doi: 10.1038/nature13379

Extended Data Figure 2. Non-functional DDX31:GFI1B fusion transcripts detected by RNA-seq.

Extended Data Figure 2

(a) A complex SV on 9q34 in ICGC_MB9 resulted in expression of DDX31 (exon 19) fused to GFI1B (intron 2, antisense orientation). Note the intronic reads in GFI1B after the fusion breakpoint. (b) 9q34 inversions in ICGC_MB247 resulted in expression of DDX31 (exon 19) fused to GFI1B (exon 2, sense orientation). This fusion transcript included a frameshift, inferred to generate a C-terminal-truncated DDX31 protein and no GFI1B protein from this fused allele.