Table 1. Statistical indicators for revealed dependence of the proteasome parameters in breast samples on simultaneous effect of clinical-pathological factors.1.
| Simultaneous effect of clinical-pathological factors | ||||
| Expression of proteasome subunit | Disease stage and factor of ERα absence or ERα presence | Metastasis and histological tumor type | ||
| F (DF)2 | p 3 | F (DF)2 | p 3 | |
| LMP2 in tumor | 4.25 (2.36) | 0.022 | 2.17 (4.29) | 0.097 |
| LMP7 in tumor | 0.71 (2.36) | 0.496 | 4.16 (4.29) | 0.009 |
| LMP7 in adjacent tissue | 46.00 (2.36) | 1,21×10−10 | 16.44 (4.29) | 3.86×10−7 |
| Rpt6 in tumor | 11.30 (2.36) | 1.56×10−4 | 3.77 (4.29) | 0.014 |
| Rpt6 in adjacent tissue | 25.13 (2.36) | 1.47×10−7 | 8.07 (4.29) | 1.68×10−4 |
1
Multiple GLM (generalized linear models) analysis was applied;
2
F (DF), F-test value for indicated pair of interacting signs (Degrees of Freedom);
3
p, statistical significance of observed effects.