A, Mean and SEM numbers of orexin-immunoreactive (IR) and MCH-IR neurons in LH from two separate series of hypothalamic sections processed using peroxidase immunohistochemistry.; B, Mean and SEM active and inactive nosepokes across extinction training; C, Mean and SEM number of active and inactive nosepokes on test for renewal (ABA); D, Mean and SEM number of active and inactive nosepokes on test for extinction (ABB); E, Mean and SEM number food intake during pre-test and test; F, Mean and SEM active and inactive nosepokes during re-training of self-administration; p<.05. G, Location of microinjection tips in AcbSh; H, Photomicrograph of representative microinjection tip in AcbSh.