Table 2. Effect of COMP-Ang1 combined BMP-2 on ischemic osteonecrosis in femoral heads as assessed byMicro-CT.

	Sham	BSA	BMP-2	BMP-2+ COMP-Ang1
BV(mm3)	10.4±3.3	4.5±2.15a	5.9±1.9b	9.9±1.0c,d,e
BV/TV(%)	52.0±6.5	24.5±3.1a	35.8±7.4b	61.9±5.6c,d,e
Tb.N(mm−1)	2.1±0.4	0.9±0.4a	1.4±0.06b	3.2±0.6c,d,e
Tb.Sp(μm)	239.1±0.3	735.4±0.3a	459.1±0.5b	129.2±0.9c,d,e
Tb.Th (μm)	36.7±0.7	83.2±0.9a	62.6±0.4b	92.0±0.5c,d,e

All measurements are expressed as the mean ± SEM. BV, bone volume; TV, tissue volume; Tb.N, trabecular number; Tb.Sp, trabecular separation; Tb.Th, trabecular thickness.

^a, p<0.01 vs. Sham; ^b, p<0.01 vs. Sham; ^c, p<0.05 vs. Sham; ^d, p<0.01 vs. BSA; ^e, p<0.01 vs. BMP-2.