Table 2. Proteins identified only in the endolymphatic sac luminal fluid of Meniere's disease patients by LC-MS/MS.
Accession number | Description | Max coverage (%) | Max protein score |
gi|34536154 | Unnamed protein product | 26.3 | 387 |
gi|56786126 | AF1 non-allergic IgE heavy chain IGHV3-74 | 27.4 | 133 |
gi|1871491 | IgM | 41.4 | 180 |
gi|886286 | This CDS feature is included to show the translation of the corresponding V_region. Present translation qualifiers on V_region features are illegal | 32.6 | 102 |
gi|21668608 | Immunoglobulin heavy chain VHDJ region | 34.2 | 69 |
gi|33319532 | Ig heavy chain variable region; VH3 family | 52.5 | 117 |
gi|33319348 | Ig heavy chain variable region; VH3 family | 21.7 | 112 |
gi|4323924 | Immunoglobulin kappa light chain variable region | 29 | 44 |
gi|1621457 | Interferon regulatory factor 7 | 9.3 | 64 |
Protein searches were conducted in MASCOT (version 2.2.04) using the NCBI database. The search parameters were as follows: 1) Enzyme specificity – Trypsin; 2) Maximum missed cleavages –1; 3) Carbamidomethyl (C); Oxidation (M) as variable modifications; MASCOT results were filtered using a protein probability value of less than 0.05. Individual peptide sequences and scores were provided as Table S1.