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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Am J Hematol. 2014 Jul 22;89(10):954–963. doi: 10.1002/ajh.23786

Figure 8. In vivo rapamycin treatment improves β globin expression in β-thalassemia erythroblasts.

Figure 8

WT and Th3/+ mice treated with rapamycin (4 mg/kg*day) or control vehicle for two weeks. QRT-PCR expression analysis of globin genes in WT and Th3/+ bone marrow erythroblasts from Gates I to IV. QRT-PCR expression analysis was performed using Fluidigm microfluidics technology and quantification of target genes is relative to β actin. Results are mean ± SEM of 3 cDNAs, each generated from one mouse. Veh: vehicle, Rapa: Rapamycin.