Table 3.
Reoccurrence and survival data
| All tumors | TC | AC | LCNEC | |
|---|---|---|---|---|
| Clinical status at last f/u | ||||
| Alive without recurrence | 35 | 30 | 5 | 0 |
| Alive with recurrence | 2 | 0 | 1 | 1 |
| Alive, unknown | 7 | 6 | 0 | 1 |
| Died with disease | 8 | 0 | 1 | 7 |
| Died of other causes | 2 | 2 | 0 | 0 |
| Died, unknown cause | 1 | 1 | 0 | 0 |
| Median disease free survival (months) † | NR | NR | 35.5 | 10.1 |
| Hazard ratio | <0.01 | 0.10 | 1.00 | |
| Confidence interval (95%) | - | 0.01-0.57 | - | |
| P-value | - | <0.0001 | 0.0063 | - |
| Mean DFS follow-up (months) | 20.2 | 21.9 | 21.9 | 12.0 |
| Median survival (months) | NR | NR | NR | 19.7 |
| Hazard ratio | 0.06 | 0.08 | 1.00 | |
| Confidence interval (95%) | 0.01-0.24 | 0.00-0.54 | - | |
| P-value | - | <0.0001 | 0.0070 | - |
| Mean OS follow-up (months) | 29.6 | 31.4 | 34.3 | 18.3 |
†p = 0.0168, DFS, TC vs. AC.
AC = atypical carcinoid; TC = typical carcinoid; LCNEC = large cell neuroendocrine carcinoma.