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. Author manuscript; available in PMC: 2015 Oct 21.
Published in final edited form as: J Am Coll Cardiol. 2014 Oct 21;64(16):1681–1694. doi: 10.1016/j.jacc.2014.06.1204

Figure 3. Expression of Angiogenic, Integrin, and Inflammatory Factors.

Figure 3

Quantitative reverse transcriptase polymerase chain reaction was performed to measure the level of gene expression from cultured and uncultured CD31+ cells. Various angiogenic (A), cell adhesion (integrin) (B), proinflammatory (C), and anti-inflammatory (D) factors were up-regulated or down-regulated in the cultured groups compared with the uncultured group (n = 4 each; *p < 0.05; **p < 0.01). Individual values were normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (+p < 0.05, HC vs. EC; ‡p < 0.01, HC vs. EC; §p < 0.05, EC vs. MC; p < 0.01, EC vs. MC; ‖p < 0.01, MC vs. HC). AKT1 = Ak strain transforming oncogene; ANGPT1/2 = angiopoietin 1/2;CCL2 = chemokine (C-C motif) ligand 2; FGF2 = basic fibroblast growth factor; HGF = hepatocyte growth factor; IFNG = interferon gamma; IGF1 = insulin-like growth factor 1; IL(n) = interleukin (n); IL1R1 = interleukin 1 receptor, type1; ITGA5/6 = integrin alpha-5/-6; ITGB1/2 = integrin beta-1/-2; LIF = leukemia inhibitory factor; MMP9 = matrix metallopeptidase 9; PDGFB = platelet-derived growth factor beta; PlGF = placental growth factor; TGFB1 = transforming growth factor beta-1; TNF = tumor necrosis factor; TNFRSF1A = tumor necrosis factor receptor 1A; VEGFA = vascular endothelial growth factor A. Other abbreviations as in Figure 1.