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. 2014 Nov;20(11):1815–1826. doi: 10.1261/rna.044321.114

FIGURE 2.

FIGURE 2.

SHAPE analysis gives an uncertain model for the 126–235 RNA. (A) Secondary structure prediction using one-dimensional SHAPE (1M7) data. Nucleotides are colored with SHAPE reactivities. Crystallographic pairings missing in this model and new noncrystallographic pairings are drawn as yellow and gray lines, respectively. Percentage labels give bootstrap support values. (B) Bootstrap support values for each base-pair shown as grayscale shading. The data presented are symmetrical, but with positions corresponding to crystallographic and alternative pairings labeled separately on the bottom left and top right, respectively. Labeled open circles mark the predicted pairings from the three models shown in Figure 1. Blue arrows mark a range of further alternative pairings.