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Results of MRM Imaging. (a) Ion maps for the several unique transitions for raltegravir (RAL) that were observed from the targeted MS2 IR-MALDESI MSI experiment. The colocalization of all of the transitions demonstrates the increased selectivity that can be realized with targeted MS2 imaging techniques. (b) Comparison of the ion abundance ratios for selected transitions of raltegravir for both IR-MALDESI and LC-MS/MS.
