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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Mod Pathol. 2014 Apr 18;27(11):1438–1446. doi: 10.1038/modpathol.2014.57

Figure 1. Next-generation sequencing for minimal residual disease detection of NPM1 mutations.

Figure 1

Comparison of next-generation sequencing (dash) versus flow cytometry (circle) results using cell mixtures of the NPM1-mutation positive OCI-AML3 cell line diluted into normal marrow. Graph depicts four technical replicates for each next-generation sequencing sample, with each set of technical replicates sequenced on three separate sequencing runs (red, green, or blue). Intra- and inter-run reproducibility data are shown in Table 2.