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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: J Immunol. 2014 Sep 22;193(9):4303–4311. doi: 10.4049/jimmunol.1401505

Figure 6.

Figure 6

Bcl-3 overexpression promotes T cell priming and DC survival. (A) WT and Tg BMDCs were treated and co-cultured with CFSE-labeled OT-II cells and T cells analyzed as in Figure 1A (standard conditions and analysis). Data shown as mean ±SEM; n=3/group. (B) WT and Tg BMDCs were treated and co-cultured as in (A), then cells stained for CD11c, Annexin V and 7-AAD and analyzed by flow cytometry after gating on CD11c. Data shown as mean of % live DCs ±SEM; n=3/group. (C) WT and Tg mice were injected with LPS (30μg) or PBS i.v.; splenocytes were isolated 48h later and stained and gated for CD11c and MHC-II. Data shown as mean of absolute numbers ±SEM; n=5 mice/group. *P<0.05, **P<0.01 and ***P<0.0001