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. 2014 Oct 2;10(10):1116–1127. doi: 10.7150/ijbs.10236

Figure 2.

Figure 2

Characterization of prostate tumor growth in 3PEKOT and 3FloxT mice. A. Similar body weights of 3PEKOT and 3FloxT mice (n=10 for each group) at ages indicated. B. The genitourinary tract (GU) weights of 3PEKOT and 3FloxT mice at different ages (n=10 in each group). GU weight trended lower in 3PEKOT versus 3FloxT mice at 24 and 30 weeks, but the difference did not reach statistical significance. C. The average prostate tumor weights of these two groups of mice were also not statistically different. D. The macroscopic gross pictures of the upper genitourinary tracts of 24-week-old 3PEKOT and 3FloxT mice. Arrows indicate prostate tumors. E. The macroscopic gross pictures of dissected prostates with tumors of 24-week-old 3PEKOT and 3FloxT mice. Of note, one of the anterior lobs in this 3FloxT mouse has bigger tumor, which was not consistently observed in all mice at this stage.