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. 2014 Oct 2;10(10):1116–1127. doi: 10.7150/ijbs.10236

Figure 3.

Figure 3

Increased NE tumor incidence in 3PEKOT mice at 30 weeks of age. A. Three types of tumor lesions developed in TRAMP mice, including atypical hyperplasia (AH), neuroendocrine tumor (NE) and phyllodes (PHY). AH tumor cells express AR and SRC-3 but not Syp. NE tumor cells express Syp and SRC-3 but not AR. PHY tumor cells express AR but not Syp. The images of AH were taken from a tumor section of 3FloxT mouse, while the images of NE and PHY were taken from tumor sections of 3PEKOT mice. B. The frequency of each tumor type in the tumors of 24 and 30-week-old 3FloxT and 3PEKOT mice. See text for the results of statistical analysis.