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SRC-3+ NE tumors are commonly observed in 30-week-old 3PEKOT mice. A. IHC for AR and Syp (brown) in tumor sections of 30 week-old 3FloxT, 3PEKOT and SRC-3-/-;TRAMP mice. AH, atypical hyperplasia; NE, neuroendocrine tumor. B. IHC for SV40 T antigen, AR, SRC-3 and Syp (brown) in adjacent sections of a NE tumor from a 30-week-old 3PEKOT mouse.
