Table 1.
Kinetics table comparing the 1/α, sensitivity, and C1/2 for mutants
Mutant | C1/2 (μM) | 1/α (μM) |
---|---|---|
G22S | 0.98 ± 0.05 | 0.5 ± 0.05 |
WT | 2.31 ± 0.15 | 0.91 ± 0.27 |
G22C | 3.88 ± 0.12 | 1.28 ± 0.35 |
Data are means ± se. Sensitivity indicates the amount of LPC required for an e-fold change in percentage release, and C1/2, indicates the LPC concentration at which 50% of the final release occurs, derived by fitting with the Boltzmann function.