Table 4. KIR and HLA-C Associations in the Interferon-Treated Individuals.
SVR n (%) | No SVR n (%) | P Value (Pc) | OR (95% CI) | |
---|---|---|---|---|
Number of patients | 107 | 101 | ||
KIR2DL2 | 54 (50.5) | 60 (59.4) | 0.20 | |
KIR2DL3 | 98 (91.6) | 90 (89.1) | 0.54 | |
Group 1 HLA-C | 94 (87.9) | 76 (75.2) | 0.02 (>0.1) | 2.4 (1.1-5.3) |
Group 2 HLA-C | 63 (58.9) | 67 (66.3) | 0.27 | |
KIR2DL2-C1 | 46 (43.0) | 40 (39.6) | 0.62 | |
KIR2DL3-C1 | 88 (82.2) | 68 (67.3) | 0.01 (0.1) | 2.3 (1.2-4.3) |
KIR2DL3-C1 homozygous | 18 (16.8) | 13 (12.9) | 0.64 | |
KIR2DL3-C1 heterozygous | 70 (65.4) | 55 (54.4) | 0.11 |