Table 2.

Effect on vertebral fracture rates (from randomized controlled trials)

	Osteopenia	Osteoporosis	Established
Raloxifene	●	■	■
Alendronate	NA	■	■
Risedronate	NA	●	■
Ibandronate	NA	■	■
Zoledronate	NA	■	■
Teriparatide	NA	NA	■
Strontium ranelate	●	■	■
Denosumab	NA	■	■

■ Denotes a preplanned analysis in the entire study population; ●Denotes a post hoc analysis. NA: No evidence available. Adapted from: Body et al[12].