Table 1.

Three protocols for prevention of recurrent hepatitis B virus infection after liver transplantation

HBIG-indefinite (HBIG continued for life)	HBIG 10000 IU iv during anhepatic phase;
	then 5000 IU iv daily for 5 d; followed by 800 IU im monthly indefinitely
	Plus
	ETV or TFV indefinitely
HBIG-light (HBIG for first 6 mo only)	HBIG 10000 IU iv during anhepatic phase;
	then 5000 IU iv daily for 5 d; followed by 800 IU im monthly for 6 mo
	Plus
	ETV and/or TFV indefinitely
HBIG-free (No HBIG)	ETV and/or TFV indefinitely

ETV: Entecavir; HBIG: Hepatitis B immune globulin; im: Intramuscular; iv: Intravenous; TFV: Tenofovir. The appropriate annual costs of these are set out in Table 2.