Table 2.
Approximate annual costs ($USD) for three post-transplant protocols for hepatitis B virus prophylaxis
Costs for the first year | |||||||||
HBIG-indefinite | HBIG 10K | 7051 | 5K IU | $17628 | 800 IU monthly | $6723 | ETV, TFV | $9900 | $41302 ($31059-$51545) |
HBIG-light | HBIG 10K | 7051 | 5K IU | $17628 | 800 IU × 6 monthly | $3385 | ETV, TFV | $9900 | $37964 ($28549-$47379) |
HBIG-free | None | None | None | None | None | None | ETV, TFV | $9900 | $9900 |
Costs in the subsequent years | |||||||||
HBIG-indefinite | None | None | None | None | 800 IU monthly | $6723 | ETV, TFV | $9900 | $16623 ($14097-$19149) |
HBIG-light | None | None | None | None | None | None | ETV, TFV | $9900 | $9900 |
HBIG-free | None | None | None | None | None | None | ETV, TFV | $9900 | $9900 |
ETV: Entecavir; HBIG: Hepatitis B immunoglobulin; iv: Intravenous; im: Intramuscular; 1K: 1000 units; 10K: 10000 units; TFV: Tenofovir; NAs: Nucleotide analogues. These costs will be approximately doubled if two NAs are administered.