Figure 2.

Detection of gene expression differences from ratio data that are lognormally distributed. Frequencies of affirmative significance calls with six analytical models are plotted against the factor of gene expression difference. Symbols represent the analysis model used: AC(+), AV(◇), AU(O), MC(×), MV(□), and MU(△). Diagrams correspond to ratio data simulated with A) and B) equal variance in the two nodes of the experimental design, and C) and D) standard deviations proportional to expression level in each node.