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GW4064 reduces hepatic proinflammatory cytokine expression in a murine nonalcoholic fatty liver disease model. RNA was extracted from the liver tissues of normal diet, high-fat (HF), HF + lipopolysaccharide (LPS), and HF + GW4064 + LPS mice. Real-time polymerase chain reaction was used to determine the mRNA levels of Tnf, Mcp1, Il1b, Il6, Il17, and Ifng. aP < 0.05, bP < 0.01 vs HF + LPS group.
