Table 1.
Number of studies | Number of subjects | RR | 95% CI | I2 value | NNT | 95% CI | |
All studies# | 6 | 361 | 1.13 | 0.97 to 1.31 | 58% | N/A | N/A |
Risk of bias of trials | |||||||
Moderate | 5 | 301 | 1.14 | 0.95 to 1.39 | 66% | N/A | N/A |
High | 1 | 60 | 1.08 | 0.88 to 1.32 | N/A | N/A | N/A |
Route of administration | |||||||
Via oral | 4 | 231 | 1.08 | 0.84 to 1.39 | 67% | N/A | N/A |
Via rectal | 2 | 130 | 1.22 | 0.93 to 1.59 | 70% | N/A | N/A |
Definition of response to therapy | |||||||
Clinical alone | 4 | 301 | 1.07 | 0.91 to 1.25 | 65% | N/A | N/A |
Clinical + Imaging | 2 | 60 | 1.45 | 1.11 to 1.91 | 0% | 3.2 | 2 to 7.7 |
Aetiology | |||||||
Postoperative | 3 | 190 | 1.15 | 1.01 to 1.31 | 35% | 7.7 | 4.2 to 50 |
Non-postoperative | 3 | 171 | 1.11 | 0.72 to 1.73 | 78% | N/A | N/A |
N/A, not applicable;
refers to the studies dichotomous data can be extracted from.