Table 2.
Ingredients and targets of Flos Lonicerae
| Geraniol | ||
| ID | Gene Name | Function |
| 1832253 | arachidonate 15-lipoxygenase | Metabolic |
| Luteolin | ||
| ID | Gene Name | Function |
| 10864009 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
Infection |
| 13399304 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
Infection |
| 6274552 | signal transducer and activator of transcription 1, 91kDa | Infection |
| 24497585 | aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) |
Metabolic |
| 1351933 | amylase, alpha 1A (salivary); amylase, alpha 1B (salivary); amylase, alpha 1C (salivary) |
Metabolic |
| 154426292 | arachidonate 12-lipoxygenase | Metabolic |
| 1832253 | arachidonate 15-lipoxygenase | Metabolic |
| 49037474 | calmodulin 3 (phosphorylase kinase, delta); calmodulin 2 (phosphorylase kinase, delta); calmodulin 1 (phosphorylase kinase, delta) |
Metabolic |
| 4503385 | dopamine receptor D2 | Metabolic |
| 4503895 | galactokinase 1 | Metabolic |
| 1724069 | glucagon-like peptide 1 receptor | Metabolic |
| 119393891 | glucosidase, alpha; acid | Metabolic |
| 496369 | glucosidase, beta; acid (includes glucosylceramidase) | Metabolic |
| 18860839 | multiple endocrine neoplasia I | Metabolic |
| 20070193 | nuclear receptor subfamily 5, group A, member 1 | Metabolic |
| 2851402 | opioid receptor, mu 1 | Metabolic |
| 129483 | phospholipase A2, group IIA (platelets, synovial fluid) | Metabolic |
| 131467 | protein tyrosine phosphatase, non-receptor type 1 | Metabolic |
| 3719421 | similar to Werner syndrome protein; Werner syndrome, RecQ helicase-like |
Metabolic |
| 74732700 | solute carrier family 22 (organic anion/urate transporter), member 12 |
Metabolic |
| 4503351 | DNA (cytosine-5-)-methyltransferase 1 | Immune |
| 2358024 | T-cell receptor alpha constant; T-cell receptor alpha locus; T-cell receptor alpha variable 20; T-cell receptor delta locus; T-cell receptor delta variable 2 |
Immune |
| 126407 | arachidonate 5-lipoxygenase | Immune |
| 171543895 | ataxin 2 | Immune |
| 37622910 | cholinergic receptor, muscarinic 1 | Immune |
| 4503779 | formyl peptide receptor 1 | Immune |
| 67191027 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
Immune |
| 4826834 | matrix metallopeptidase 14 (membrane-inserted) | Immune |
| 115298672 | neutrophil cytosolic factor 1; neutrophil cytosolic factor 1C pseudogene |
Immune |
| 281185512 | protein kinase C, eta | Immune |
| 4506755 | retinoid X receptor, alpha | Immune |
| 13272532 | signal transducer and activator of transcription 3 (acute-phase response factor) |
Immune |
| 18418623 | SMAD family member 3 | Infection, metabolic |
| 1709543 | acid phosphatase 1, soluble | Infection, metabolic, immune |
| 4501969 | adrenergic, beta-2-, receptor, surface | Infection, metabolic, immune |
| 90421313 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
Infection, metabolic, immune |
| 117139 | cytochrome P450, family 1, subfamily A, polypeptide 1 | Infection, metabolic, immune |
| 4503219 | cytochrome P450, family 2, subfamily C, polypeptide 19 | Infection, metabolic, immune |
| 40805836 | cytochrome P450, family 2, subfamily D, polypeptide 6 | Infection, metabolic, immune |
| 31933 | glutathione S-transferase mu 1 | Infection, metabolic, immune |
| 134039205 | glyoxalase I | Infection, immune |
| 12803275 | heat shock 70kDa protein 1A; heat shock 70kDa protein 1B | Infection, metabolic, immune |
| 1170955 | macrophage migration inhibitory factor (glycosylation-inhibiting factor) |
Infection, metabolic, immune |
| 34577122 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
Infection, immune |
| 3915797 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
Infection, metabolic, immune |
| 4507593 | tumor necrosis factor (ligand) superfamily, member 10 | Infection, immune |
| 63054845 | vitamin D (1,25-dihydroxyvitamin D3) receptor | Infection, metabolic, immune |
| 544152 | hydroxysteroid (17-beta) dehydrogenase 2 | Infection, metabolic |
| 32879895 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
Infection, metabolic |
| 155969707 | insulin-degrading enzyme | Infection, metabolic |
| 40807040 | microphthalmia-associated transcription factor | Infection, metabolic |
| 118607 | NAD(P)H dehydrogenase, quinone 1 | Metabolic, immune |
| 219518789 | NLR family, pyrin domain containing 3 | Metabolic, immune |
| 113596 | aldo-keto reductase family 1, member B1 (aldose reductase) | Metabolic, immune |
| 116734717 | alkaline phosphatase, liver/bone/kidney | Metabolic, immune |
| 113830 | androgen receptor | Metabolic, immune |
| 73915100 | cytochrome P450, family 1, subfamily A, polypeptide 2 | Metabolic, immune |
| 48429256 | cytochrome P450, family 1, subfamily B, polypeptide 1 | Metabolic, immune |
| 6686268 | cytochrome P450, family 2, subfamily C, polypeptide 9 | Metabolic, immune |
| 10835013 | estrogen receptor 2 (ER beta) | Metabolic, immune |
| 4503951 | glucokinase (hexokinase 4) | Metabolic, immune |
| 31077205 | hepatocyte nuclear factor 4, alpha | Metabolic, immune |
| 3041727 | peroxisome proliferator-activated receptor alpha | Metabolic, immune |
| Eugenol | ||
| ID | Gene Name | Function |
| 32307126 | nuclear receptor coactivator 3 | Metabolic |
| 4826834 | matrix metallopeptidase 14 (membrane-inserted) | Immune |
| 11950843 | melanocortin 4 receptor | Infection, metabolic |
| Isoeugenol | ||
| ID | Gene Name | Function |
| 5730106 | chemokine (C-X-C motif) receptor 6 | Infection |
| 32307126 | nuclear receptor coactivator 3 | Metabolic |
| 4826834 | matrix metallopeptidase 14 (membrane-inserted) | Immune |
| 11950843 | melanocortin 4 receptor | Infection, metabolic |
| 113596 | aldo-keto reductase family 1, member B1 (aldose reductase) | Metabolic, immune |
| 4503951 | glucokinase (hexokinase 4) | Metabolic, immune |
| Chlorogenic Acid | ||
| ID | Gene Name | Function |
| 119393891 | glucosidase, alpha; acid | Metabolic |
| 281185512 | protein kinase C, eta | Immune |
| 219518789 | NLR family, pyrin domain containing 3 | Metabolic, immune |