Table 5.
Ingredients and targets of Scutellaria baicalensis Georgi
| Oroxylin a | ||
| ID | Gene Name | Function |
| 10864009 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
Infection |
| 24497585 | aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) |
Metabolic |
| 1832253 | arachidonate 15-lipoxygenase | Metabolic |
| 4503385 | dopamine receptor D2 | Metabolic |
| 1724069 | glucagon-like peptide 1 receptor | Metabolic |
| 119393891 | glucosidase, alpha; acid | Metabolic |
| 496369 | glucosidase, beta; acid (includes glucosylceramidase) | Metabolic |
| 126407 | arachidonate 5-lipoxygenase | immune |
| 171543895 | ataxin 2 | immune |
| 37622910 | cholinergic receptor, muscarinic 1 | immune |
| 67191027 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | immune |
| 4826834 | matrix metallopeptidase 14 (membrane-inserted) | immune |
| 281185512 | protein kinase C, eta | immune |
| 4506755 | retinoid X receptor, alpha | immune |
| 13272532 | signal transducer and activator of transcription 3 (acute-phase response factor) |
immune |
| 117139 | cytochrome P450, family 1, subfamily A, polypeptide 1 | Infection, metabolic, immune |
| 4503219 | cytochrome P450, family 2, subfamily C, polypeptide 19 | Infection, metabolic, immune |
| 40805836 | cytochrome P450, family 2, subfamily D, polypeptide 6 | Infection, metabolic, immune |
| 31933 | glutathione S-transferase mu 1 | Infection, metabolic, immune |
| 134039205 | glyoxalase I | Infection, immune |
| 34577122 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Infection, immune |
| 3915797 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
Infection, metabolic, immune |
| 4507593 | tumor necrosis factor (ligand) superfamily, member 10 | Infection, immune |
| 63054845 | vitamin D (1,25-dihydroxyvitamin D3) receptor | Infection, metabolic, immune |
| 219518789 | NLR family, pyrin domain containing 3 | Metabolic, immune |
| 48429256 | cytochrome P450, family 1, subfamily B, polypeptide 1 | Metabolic, immune |
| 10835013 | estrogen receptor 2 (ER beta) | Metabolic, immune |
| 4503951 | glucokinase (hexokinase 4) | Metabolic, immune |
| 31077205 | hepatocyte nuclear factor 4, alpha | Metabolic, immune |
| 121069 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
Metabolic, immune |
| 3041727 | peroxisome proliferator-activated receptor alpha | Metabolic, immune |
| Baicalein | ||
| ID | Gene Name | Function |
| 10864009 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
Infection |
| 13399304 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
Infection |
| 24497585 | aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4) |
Metabolic |
| 154426292 | arachidonate 12-lipoxygenase | Metabolic |
| 1832253 | arachidonate 15-lipoxygenase | Metabolic |
| 49037474 | calmodulin 3 (phosphorylase kinase, delta); calmodulin 2 (phosphorylase kinase, delta); calmodulin 1 (phosphorylase kinase, delta) |
Metabolic |
| 4503385 | dopamine receptor D2 | Metabolic |
| 4503895 | galactokinase 1 | Metabolic |
| 119393891 | glucosidase, alpha; acid | Metabolic |
| 496369 | glucosidase, beta; acid (includes glucosylceramidase) | Metabolic |
| 126407 | arachidonate 5-lipoxygenase | immune |
| 171543895 | ataxin 2 | immune |
| 37622910 | cholinergic receptor, muscarinic 1 | immune |
| 67191027 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | immune |
| 4826834 | matrix metallopeptidase 14 (membrane-inserted) | immune |
| 281185512 | protein kinase C, eta | immune |
| 4506755 | retinoid X receptor, alpha | immune |
| 13272532 | signal transducer and activator of transcription 3 (acute-phase response factor) |
immune |
| 117139 | cytochrome P450, family 1, subfamily A, polypeptide 1 | Infection, metabolic, immune |
| 4503219 | cytochrome P450, family 2, subfamily C, polypeptide 19 | Infection, metabolic, immune |
| 40805836 | cytochrome P450, family 2, subfamily D, polypeptide 6 | Infection, metabolic, immune |
| 134039205 | glyoxalase I | Infection, immune |
| 34577122 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | Infection, immune |
| 3915797 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
Infection, metabolic, immune |
| 4507593 | tumor necrosis factor (ligand) superfamily, member 10 | Infection, immune |
| 63054845 | vitamin D (1,25-dihydroxyvitamin D3) receptor | Infection, metabolic, immune |
| 544152 | hydroxysteroid (17-beta) dehydrogenase 2 | Infection, metabolic |
| 32879895 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
Infection, metabolic |
| 219518789 | NLR family, pyrin domain containing 3 | Metabolic, immune |
| 48429256 | cytochrome P450, family 1, subfamily B, polypeptide 1 | Metabolic, immune |
| 10835013 | estrogen receptor 2 (ER beta) | Metabolic, immune |
| 4503951 | glucokinase (hexokinase 4) | Metabolic, immune |
| 121069 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
Metabolic, immune |
| 3041727 | peroxisome proliferator-activated receptor alpha | Metabolic, immune |