Table 3.

Effect of Sepia officinalis ink extract (IE) and Amphotericin B (AMB) on AST and ALT activities in neutropenic mice with invasive pulmonary aspergillosis (IPA).

Groups	AST (U/ml)		ALT (U/ml)
	24 h	72 hs	24 h	72 hs
Infected untreated group	156.8 ± 8.37	147.6 ± 2.15	112 ± 1.64	112.4 ± 4.13
AMB group	73.4 ± 5.48a	85.8 ± 4.56a	87.4 ± 2.83a	85.2 ± 9.47a
IE group	87.4 ± 7.97a	92.2 ± 3.96ab	65.2 ± 3.42a	68.4 ± 12.86a
IE + AMB group	70.6 ± 7.31a	64.8 ± 10.37a	91 ± 8.34	93 ± 5.87
ANOVA Two way
Treatment	p<0.0001		p<0.0001
Time	NS		NS
Interaction	p<0.01		NS
(treatment X time intervals)

Data are presented as mean ± SEM (n=5 in each group).

^aSignificantly different from infected untreated group at p<0.05.

^bSignificantly different from AMB treated group at p<0.05.