Table 1.
Cytotoxicity towards MCF-7 breast cancer cell of flower extracts of B. kockiana
| Extracts | Cytotoxic activity (µg/mL) | Phytochemical screening |
||
| GI50 | TGI | LC50 | ||
| Hexane | >100 | >100 | >100 | n.t. |
| Dichloromethane | >100 | >100 | >100 | n.t. |
| Ethyl acetate | 26.0 ± 1.8a | 38.9 ± 2.2a | 51.8 ± 4.8a | Tannin |
| Methanol | 31.5 ± 2.6b | 49.0 ± 6.1b | 66.6 ± 9.5b | Tannin, flavonoid |
| n-Butanol | 58.6 ± 1.3c | >100 | >100 | n.t. |
| Water | >100 | >100 | >100 | n.t. |
Note: GI50 = concentration that inhibits growth by 50%; TGI = concentration that inhibits growth by 100%; LC50 = concentration that kills 50% of treated cells. Data are expressed as means ± SD obtained from 3 independent experiments. “n.t.” represents not tested. For each column, values followed by the same letter (a–b) are statistically insignificant (P> 0.05) as determined by ANOVA.