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. 2014 Jun 26;4(2):46–58. doi: 10.5662/wjm.v4.i2.46

Table 1.

Dynamic contrast-enhanced magnetic resonance imaging parameter correlations with physiological parameters at breast tissue

Ref. Correlation
Direction of correlation P
Physiological parameter DCE-MRI measurement
Buadu et al[76], 1996 MVD Amplitude + < 0.01
Slope maximum + < 0.01
Enhancement Maximum time - < 0.01
Tumor size .. NS
Stomper et al[77], 1996 DNA S-phase percentage Signal enhancement amplitude .. NS
Signal enhancement rate .. NS
Signal washout .. NS
Hulka et al[78], 1997 Tumor grade RSI + < 0.01
Matsubayashi et al[79], 2000 Peripheral-central MVD ratio Early rim enhancement + 0.048
Peripheral-central fibrosis ratio Early rim enhancement - < 0.01
Central-peripheral fibrosis ratio Delayed rim + 0.013
Gianfelice et al[80], 2003 Residue tumor percentage after MRIgFUS ISI + NR
MDF + NR
PEI + NR
Su et al[81], 2003 VEGF Apparent Vb .. NS
In-flux rate and distribution volume in interstitial space (VeK1) .. NS
Out-flux rate (K2) .. NS

NS: Not significant; NR: Not reported; RSI: Relative signal intensity; MVD: Microvessel density; ISI: Increase in signal intensity; MDF: Maximum difference function; PEI: Positive enhancement interal; Vb: Vascular volume; VEGF: Vascular endothelial growth factor.