Table 1.
Growth Inhibition values for compounds 2–5 against TK-10, UACC-62 and MCF-7 cell lines.
| Compound | Dose-response parameters |
Line 1 (TK-10) Renal |
Line 2 (UACC-62) Melanoma |
Line 1 (MCF-7) Breast |
| 2 | GI50 | 50.57 | 31.01 | 45.51 |
| TGI | N/A | 60.28 | 78.40 | |
| LC50 | N/A | 89.55 | N/A | |
| 3 | GI50 | 55.44 | 40.14 | 69.05 |
| TGI | N/A | 90.41 | N/A | |
| LC50 | N/A | N/A | N/A | |
| 4 | GI50 | 69.89 | 53.34 | 66.19 |
| TGI | N/A | N/A | N/A | |
| LC50 | N/A | N/A | N/A | |
| 5 | GI50 | 45.81 | 27.35 | 31.92 |
| TGI | 91.06 | 52.49 | 57.22 | |
| LC50 | N/A | 77.62 | 82.52 | |
| Etoposide | GI50 | 4.88 | 0.74 | 0.57 |
| TGI | 36.77 | 16.41 | N/A | |
| LC50 | 85.38 | 84.58 | N/A | |