Table 1.
Group | Number | Rate (%) |
---|---|---|
Sham(n=7) | 0 | 0 |
Berberine (10 mg/Kg)-treated SH(n=7) | 0 | 0 |
Kainate (n=12) | 8 | 66.6 |
Berberine (25 mg/kg)-Kainate (n=10) | 4 | 40* |
Berberine (50 mg/kg)-Kainate (n=10) | 4 | 40* |
Berberine (100 mg/kg)-Kainate (n=10) | 1 | 10** |
χ2 test
P<0.01
P<0.005 compared with Kainate group; Seizure activity was observed for five hours during the first day post-surgery.