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. 2014 Spring;5(2):124–130.

Table 2.

Numbers and rates of spontaneous seizures in each group

Group Number Rate (%)
Sham(n=7) 0 0
Berberine (10 mg/Kg)-treated SH(n=7) 0 0
Kainate (n=12) 5 41.6
Berberine (25 mg/kg)- Kainate (n=10) 5 50*
Berberine (50 mg/kg)- Kainate (n=10) 3 30**
Berberine (100 mg/kg)- Kainate (n=10) 2 20**

χ2 test

*

P<0.05

**

P<0.01 compared with Kainate group; Two weeks post-surgery, seizure activity was observed for five hours/per day during five days.