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The effect of cZnO (1, 5, 10, 20 mg/kg) on latency time to pain stimulus in hot plate test: each line show the mean ± SEM for one dose in four times (every 30 min from 0 up to 90). *P < 0.05 show significant differences between cZnO 10mg/kg and control group and +P < 0.05 show significant difference between cZnO 10 mg/kg and cZnO 1mg/kg at the time of 90 minutes.
