Fig. 1.
iEM of human biopsies. Immunogold labeling of Neph1 (arrowheads) in kidney. a Neph1 in normal human kidney, localized to the foot processes close to the SD. b Double labeling of Neph1 (10 nm; arrow) and nephrin (5 nm; arrowheads) in the foot process in normal human kidney. c, d Labeling of Neph1 in FSGS (c) and MCNS (d). P = Podocyte; E = endothelial cell. Scale bars = 300 nm (a, c, d) and 100 nm (b).