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iEM of mouse (a, b) and rat (c, d) biopsies. Immunogold labeling of Neph1 (arrowheads) in kidney. a Neph1 in normal mouse kidney, localized to the foot processes close to the SD. b Neph1 is reduced in ADR on day 14 both in areas with and those without FPE. c Neph1 in normal rat kidney, localized mainly to the SD. d Neph1 is reduced in PAN on day 4 both in areas with and those without FPE. P = Podocyte; E = endothelial cell. Scale bars = 200 nm.
