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. 2014 Jan 28;11(2):402–410. doi: 10.4314/ajtcam.v11i2.26

Table 1.

Effect of 100–400 mg/kg oral treatment of Alchornea cordifolia hydroethanolic leaf extract on paw edema in CFA-induced arthritic rats

Treatment	Day 4 (cm)	Day 8 (cm)	Day 12 (cm)	Day 16 (cm)	Day 20 (cm)	Day 24 (cm)	Day 28 (cm)
10 ml/kg DW	0.92 ± 0.15	0.53 ± 0.03	0.80 ± 0.10	0.50 ± 0.06	0.50 ± 0.06	0.50 ± 0.09	0.80 ± 0.28
100 mg/kg HEAC (Pre)	1.18 ± 0.04	0.66 ± 0.02	0.56 ± 0.14	0.40 ± 0.09	0.38 ± 0.10	0.36 ± 0.09	0.34 ± 0.08^c
200 mg/kg HEAC (Pre)	0.70 ± 0.09	0.48 ± 0.09	0.58 ± 0.15	0.45 ± 0.03	0.45 ± 0.03	0.45 ± 0.03	2.1 ± 0.00^a
400 mg/kg HEAC (Pre)	1.20 ± 0.16	0.52 ± 0.05	0.52 ± 0.05	0.42 ± 0.02	0.40 ± 0.00	0.40 ± 0.00	0.36 ± 0.02^b
200 mg/kg HEAC (Post)	1.15 ± 0.03	0.60 ± 0.04	0.60 ± 0.04	0.58 ± 0.05	0.48 ± 0.09	0.40 ± 0.06	0.37 ± 0.07^b
400 mg/kg HEAC (Post)	1.00 ± 0.14	0.48 ± 0.05	0.45 ± 0.03^a	0.40 ± 0.00	0.40 ± 0.00	0.38 ± 0.03	0.38 ± 0.03^b
3 mg/kg CELE	1.10 ± 0.04	0.55 ± 0.06	0.45 ± 0.03^a	0.43 ± 0.05	0.43 ± 0.05	0.43 ± 0.05	0.40 ± 0.04^b

^{a, b and c}

represent significant decreases at p<0.05, p<0.01 and p<0.001 on day 28, respectively, when compared to day 4 values