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. 2014 Jan 28;11(2):402–410. doi: 10.4314/ajtcam.v11i2.26

Table 2.

Effect of 100–400 mg/kg of Alchornea cordifolia hydroethanolic leaf extract on body weight changes (g) of CFA-induced arthritic rats

Treatment 4th day ΔWt 8th day ΔWt 12th day ΔWt 16th day ΔWt 20th day ΔWt 24th day ΔWt 28th day ΔWt
Control 7.67 ± 3.37 12.70 ± 4.42 17.00 ± 4.50 21.30 ± 4.66 26.30 ± 8.95 38.30 ± 8.71 36.80 ± 8.34
100 mg/kg HEAC (Pre) 8.05 ± 1.80 8.26 ± 1.80 11.80 ± 8.85 51.00 ± 15.80a 75.40 ± 17.30c 84.60 ± 15.20c 96.00 ± 15.50c
200 mg/kg HEAC (Pre) 6.75 ± 0.85 7.50 ± 1.70 20.80 ± 6.17 33.80 ± 9.78 35.50 ± 10.70 41.30 ± 12.20 51.30 ± 13.30a
400 mg/kg HEAC (Pre) 14.00 ± 4.34 23.40 ± 3.97 30.80 ± 4.57 44.60 ± 7.46a 64.40 ± 6.74b 74.60 ± 5.18c 85.40 ± 5.56c
200 mg/kg HEAC (Post) 8.80 ± 1.16 11.20 ± 3.93 13.60 ± 7.78 18.60 ± 11.80 32.20 ± 12.50 40.20 ± 13.30 47.00 ± 14.00
400 mg/kg HEAC (Post) 8.60 ± 1.44 21.20 ± 5.88 34.60 ± 10.20a 42.20 ± 12.00a 53.80 ± 15.40b 61.40 ± 15.20a 70.80 ± 15.40b
3 mg/kg CELE 8.67 ± 1.12 23.30 ± 2.85 33.70 ± 4.98a 56.20 ± 7.35b 51.80 ± 12.60b 60.80 ± 12.90a 68.20±12.90b
a, b and c

represent significant increases at p<0.05, p<0.01 and p<0.001 when compared to control value on 12th, 16th, 20th, 24th and 28th day