Table 3.
Effect of 100–400 mg/kg of hydroethanolic leaf extract of Alchornea cordifolia on the full blood count of CFA-induced arthritic rats
| Treatment (mg/kg) | WBC (103/µl) |
RBC (106/µl) |
Hb (g/dl) | PCV (%) | PLT (104/µl) | MCV(fl) | MCH (pg) | MCHC (g/dl) |
% neutrophil |
| Untreated control | 10.90 ± 2.58 |
7.32 ± 0.51 | 13.60 ± 1.03 |
41.00 ± 3.84 |
716.00 ± 25.40 |
55.90 ± 2.18 | 18.50 ± 0.26 |
33.20 ± 0.85 |
30.20 ± 4.81 |
| Arthritic control | 11.10 ± 1.05 |
7.21 ± 0.22 | 13.70 ± 0.26 |
41.40 ± 0.59 |
741.00 ± 98.10 |
57.70 ± 1.41 | 19.00 ± 0.24 |
33.00 ± 0.39 |
30.40 ± 2.32 |
| 100 mg/kg HEAC (Pre) |
15.90 ± 2.37a |
7.87 ± 0.35 | 15.10 ± 0.45 |
45.90 ± 1.63 |
548.00 ± 69.20d |
58.50 ± 1.15 | 19.20 ± 0.46 |
32.80 ± 0.20 |
30.40 ± 3.36 |
| 200 mg/kg HEAC (Pre) |
14.50 ± 2.88a |
7.59 ± 0.38 | 14.30 ± 0.61 |
45.10 ± 1.65 |
864.00 ± 59.60c |
196.00 ± 36.00c |
18.90 ± 0.25 |
31.70 ± 0.36 |
31.20 ± 3.32 |
| 400 mg/kg HEAC (Pre) |
14.40 ± 3.16a |
7.46 ± 0.26 | 14.40 ± 0.46 |
46.40 ± 1.42 |
676.00 ± 82.50 |
62.30 ± 0.92 | 19.30 ± 0.18 |
31.70 ± 0.81 |
34.30 ± 3.52 |
| 200 mg/kg HEAC (Post) |
16.30 ± 3.16a |
7.72 ± 0.42 | 14.20 ± 1.00 |
44.70 ± 2.34 |
646.00 ± 69.60 |
58.00 ± 0.49 | 18.30 ± 0.35 |
31.50 ± 0.86 |
29.70 ± 6.23 |
| 400 mg/kg HEAC (Post) |
9.88 ± 1.62 | 7.64 ± 0.35 | 13.90 ± 0.58 |
41.50 ± 1.42 |
663.00 ± 33.00 |
54.50 ± 1.26 | 18.20 ± 0.41 |
33.50 ± 0.30 |
32.80 ± 2.17 |
| 3 mg/kg CELE | 12.50 ± 0.77 |
7.72 ± 0.50 | 14.50 ± 1.01 |
45.10 ± 3.17 |
621.00 ± 47.60 |
58.50 ± 1.56 | 18.80 ± 0.50 |
32.10 ± 0.09 |
30.70 ± 4.86 |