. 2014 Jan 28;11(2):402–410. doi: 10.4314/ajtcam.v11i2.26

Table 4.

Effect of oral pretreatment with 100–400 mg/kg HEAC on liver function parameters of CFA-induced arthritic rats

Treatment	AST (U/l)	BIL (mg/dl)	CREA (mg/dl)	ALT (U/l)	UREA (mg/dl)	ALB (mg/dl)	TP (mg/dl)	CHOL (mg/dl)	TG	ALP
Untreated control	320.00 ± 51.40	5.33 ± 0.14	72.20 ± 8.76	59.50 ± 12.00	9.35 ± 1.27	40.00 ± 2.81	81.40 ± 1.33	2.51 ± 0.17	0.97±0.11	173.00±34.40
Control arthritic	390.00 ± 39.50^a	4.45 ± 0.21	55.50 ± 2.27^d	64.80 ± 1.91	9.40 ± 0.45	41.10 ± 1.06	76.60 ± 1.94	2.11 ± 0.13	0.80±0.20	215.00±32.70^a
100 mg/kg HEAC (Pre)	304.00 ± 19.50	4.35 ± 0.21	54.60 ± 1.65^d	67.30 ± 7.40	8.58 ± 0.59	42.70 ± 0.81	77.20 ± 2.09	2.47 ± 0.14	0.95±0.11	209.00±59.10
200 mg/kg HEAC (Pre)	397.00 ± 28.40^a	4.85 ± 0.07	55.70 ± 2.16^d	59.90 ± 1.66	10.00 ± 0.53	41.70 ± 1.55	76.60 ± 1.45	2.37 ± 0.24	0.61±0.07	256.00±42.00^b
400 mg/kg HEAC (Pre)	319.00 ± 21.30	4.83 ± 0.21	55.50 ± 2.71^d	57.10 ± 4.74	8.20 ± 0.78	43.90 ± 2.41	76.80 ± 2.72	2.37 ± 0.07	0.74±0.13	332.00±46.20^c
200 mg/kg HEAC (Post)	339.00 ± 8.28	4.43 ± 0.19	51.40 ± 3.37^d	64.00 ± 3.80	8.90 ± 0.65	40.30 ± 1.66	70.40 ± 1.44	2.54 ± 0.36	0.63±0.03	259.00±44.50^b
400 mg/kg HEAC (Post)	306.00 ± 25.50	4.25 ± 0.13	50.90 ± 1.13^d	55.60 ± 5.87	8.30 ± 0.65	42.00 ± 2.40	75.00 ± 3.13	2.08 ± 0.17	0.95±0.09	258.00±48.50^b
3mg/kg CELE	325.00 ± 26.40	4.73 ± 0.43	51.50 ± 5.03^d	57.90 ± 4.24	7.58 ± 0.55	39.90 ± 2.82	73.70 ± 3.67	2.43 ± 0.10	0.77±0.17	292.00±20.70^c

^{a, b and c}

represent significant increases at p<0.05, p<0.01 and p<0.001, respectively, when compared to untreated control group values and ^d represents a significant decrease at p<0.05 when compared to untreated control group