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. 2014 Jan 28;11(2):402–410. doi: 10.4314/ajtcam.v11i2.26

Table 6.

Effect of 100 – 400 mg/kg of HEAC on splenic antioxidant and glycoprotein in CFA-induced arthritic rats

Treatment GSH (U/mg protein) SOD
(U/mg protein)
CAT
(U/mg protein)
MDA
(ng/mg protein)
Nitrite Hexose sugar Sialic
Untreated control 0.56 ± 0.06 4.74 ± 1.45 16.51±3.54 0.02±0.006 2.72±0.20 473.50±28.47 119.60±10.46
Arthritic control 0.29 ± 0.08d 1.80 ± 0.41d 18.44±4.81 0.08±0.001a 4.48±1.70a 528.70±98.70 248.60±17.85b
100 mg/kg HEAC (Pre) 0.23 ± 0.03d 1.43 ± 0.28d 15.12±1.52 0.06±0.004 2.66±0.44d 567.40±6.25 90.11±9.50e
200 mg/kg HEAC (Pre) 0.27 ± 0.06d 2.04 ± 0.28a 19.38±0.81 0.03±0.005d 2.85±0.45d 378.50±20.21d 79.26±2.82e
400 mg/kg HEAC (Pre) 7.34 ± 1.53b 1.55 ± 0.09d 16.82±0.32 0.08±0.02a 2.66±0.28d 439.50±16.13d 93.55±0.78d
200 mg/kg HEAC (Post) 2.91 ± 0.97a 2.25 ± 0.27a 21.19±4.32 0.10±0.03 2.52±0.18d 509.20±20.09 67.11±9.56f
400 mg/kg HEAC (Post) 11.51±0.97c 1.76 ± 0.35d 18.09±3.90 0.06±0.01 1.54±0.00e 259.00±23.20e 70.97±15.38f
3mg/kg CELe 6.78±1.05b 1.18 ± 0.16d 13.46±1.31 0.06±0.01 3.05±0.04a 538.10±21.74 147.00±10.72a
a, b and c

represent a significant increase at p<0.05, p<0.01 and p<0.001 when compared to untreated control group while d, e and f represent significant decreases at p<0.05, p<0.01 and p<0.001 when compared to untreated arthritic rats.