Table 6.
Treatment | GSH (U/mg protein) | SOD (U/mg protein) |
CAT (U/mg protein) |
MDA (ng/mg protein) |
Nitrite | Hexose sugar | Sialic |
Untreated control | 0.56 ± 0.06 | 4.74 ± 1.45 | 16.51±3.54 | 0.02±0.006 | 2.72±0.20 | 473.50±28.47 | 119.60±10.46 |
Arthritic control | 0.29 ± 0.08d | 1.80 ± 0.41d | 18.44±4.81 | 0.08±0.001a | 4.48±1.70a | 528.70±98.70 | 248.60±17.85b |
100 mg/kg HEAC (Pre) | 0.23 ± 0.03d | 1.43 ± 0.28d | 15.12±1.52 | 0.06±0.004 | 2.66±0.44d | 567.40±6.25 | 90.11±9.50e |
200 mg/kg HEAC (Pre) | 0.27 ± 0.06d | 2.04 ± 0.28a | 19.38±0.81 | 0.03±0.005d | 2.85±0.45d | 378.50±20.21d | 79.26±2.82e |
400 mg/kg HEAC (Pre) | 7.34 ± 1.53b | 1.55 ± 0.09d | 16.82±0.32 | 0.08±0.02a | 2.66±0.28d | 439.50±16.13d | 93.55±0.78d |
200 mg/kg HEAC (Post) | 2.91 ± 0.97a | 2.25 ± 0.27a | 21.19±4.32 | 0.10±0.03 | 2.52±0.18d | 509.20±20.09 | 67.11±9.56f |
400 mg/kg HEAC (Post) | 11.51±0.97c | 1.76 ± 0.35d | 18.09±3.90 | 0.06±0.01 | 1.54±0.00e | 259.00±23.20e | 70.97±15.38f |
3mg/kg CELe | 6.78±1.05b | 1.18 ± 0.16d | 13.46±1.31 | 0.06±0.01 | 3.05±0.04a | 538.10±21.74 | 147.00±10.72a |
represent a significant increase at p<0.05, p<0.01 and p<0.001 when compared to untreated control group while d, e and f represent significant decreases at p<0.05, p<0.01 and p<0.001 when compared to untreated arthritic rats.